BEIRUT: Rebels seized an air defence base near Syria's strategic southern international highway on Saturday, activists said, bolstering access to supply routes to the capital Damascus.

The rebels on Saturday also seized several military sites along the Jordanian-Syrian border, according to the British-based Syrian Observatory for Human Rights, which has a network of informants across the country.

The developments give fighters control of about 25 km (15.5 miles) of frontier adjacent to the Israeli-occupied Golan Heights, the Observatory said, and could fuel tensions in the sensitive military zone.

Syria's southern provinces bordering Jordan and Israel have become an increasingly significant battleground as the capital comes into play, with President Bashar Assad's forces and his loyalist militias hitting back hard to prevent rebel advances.

At the air base in Deraa province, which borders Jordan, the Observatory said the brigade's commander was among those killed.

"Fighters from the Nusra Front, Yarmouk Martyrs Brigade, and other battalions seized control of the 38th division air defence base, near the town of Saida on the Damascus-Amman highway, after 16 days of fierce clashes," the Observatory said.

The Nusra Front is an Islamist militant group suspected of links to Al-Qaeda and blacklisted by the United States as a "terrorist group". Its forces, which include foreign fighters, have come to increasing prominence in the revolt.

Videos published by opposition activists showed cheering fighters driving tanks around the base and loading boxes of ammunition onto flatbed trucks. The rebels also said in the videos they had freed dozens of prisoners held at the base.

A video uploaded by the Observatory showed what it said was the body of base commander General Mahmoud Darwish lying in a pool of blood in a bathroom.

Other activist videos showed the corpses of soldiers in camouflage fatigues scattered in the grass outside the base, shot in the head.

It was not immediately possible to verify the pictures or opposition reports. The Syrian government has severely restricted access to Syria for foreign journalists and international aid groups.

Fighting also raged near the ceasefire line with Israel, which increasingly is concerned Islamist rebels may be emboldened to end the quiet on the Golan front maintained by Assad, and his father before him, during their four-decade rule.

Israel captured the Golan plateau from Syria in the 1967 Middle East war.

Rebels seized at least four military checkpoints near the Golan in southwestern Deraa province on Saturday, the Observatory said, and captured a large amount of weapons, ammunition and vehicles.

The armed struggle between rebels and forces loyal to Syrian President Bashar al-Assad has posed increasing difficulties for the 1,000-strong U.N. Disengagement Observer Force (UNDOF).

U.N. peacekeepers monitoring the line halted patrols this month after rebels held 21 Filipino observers for three days.

On Wednesday, rebels overran at least three towns near the Israeli-Syrian disengagement line but then suffered a fierce attack by militias loyal to Assad.

Rami Abdelrahman, head of the Observatory, said he recorded one of the heaviest single death tolls for rebels in the fighting near the Israeli border.

"We have 35 fighters recorded by name and at least 20 more missing, this is a huge number to be lost in a single battle and shows how hard they (Assad's forces) are fighting for these areas," Abdelrahman told Reuters.

He said the pro-government militias involved were made up of fighters from Syria's Druze minority, a sect which for some time had stayed on the sidelines of the conflict but now increasingly appears to be throwing its weight behind Assad.

Their involvement could increase sectarian bloodshed in Syria, already wracked by tensions between the Sunni Muslim majority that has led the uprising and the Alawite minority to which Assad belongs.

Tit-for-tat kidnappings and killings between the sects have become common as the uprising spiralled into a bloody civil war that has killed more than 70,000 people.

Alawite opposition campaigners, increasingly concerned for the fate of their community as fighting continues, will meet this weekend to discuss options for supporting a democratic alternative to Assad's rule and try to distance themselves from security forces attempts to crush the revolt.