United are trailing league leaders City by eight points.
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Manchester City will bid to hammer home their advantage at the top of the Premier League against Southampton, while Manchester United head to Watford hoping to cling onto the leaders' coattails in a crucial midweek programme.City underlined their determination to win the title with a gutsy 2-1 victory at Huddersfield Sunday as Pep Guardiola's side reestablished an eight-point lead over second placed United. Their Manchester rivals had closed the gap to five points with a 1-0 win against Brighton Saturday and, with City trailing to a Nicolas Otamendi own goal at halftime against Huddersfield, Jose Mourinho's men were dreaming of a title lifeline. City have now won their last 11 Premier League matches and 18 in all competitions.United have no margin for error at Vicarage Road, where Watford will aim for a repeat of last season's shock 3-1 win over Mourinho's team.
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